Senior Kaylee Brown scored 10 points including a pair of three-pointers.
Freshman point guard Ivana Catic passed out 10 assists to establish a new KU freshman single game record.
Senior Erica Hallman led KU with 19 points on a career-high six three-pointers made.
Senior Crystal Kemp posted 12 points and five rebounds. Her second rebound of the game was the 600th of her career, making her just the ninth player in KU history to reach 1,000 career points and 600 career rebounds.
The always hustling Taylor McIntosh tracked down eight rebounds while scoring nine points.
Junior guard Sharita Smith came off the bench to play outstanding pressure defense on the perimeter.